Could Germs Be Making You Fat?

REUTERS on Friday, 5th March, 2010, published some eye-opening findings! Maybe, I should say gut-wrenching findings since they actually relate to the HUMAN GUT!

According to REUTERS, researchers reported on Thursday that germs that make their home in the gut may help cause obesity and a range of health-threatening symptoms that go along with it.

It could be that certain bacteria cause inflammation that can affect appetite as well as inflammatory bowel conditions, like Crohn's disease and colitis, the researchers reported in the journal Science.

In other words, the germs make you overeat, Andrew Gewirtz of Emory University in Atlanta and colleagues reported.

"Previous research has suggested that bacteria can influence how well energy is absorbed from food, but these findings demonstrate that intestinal bacteria can actually influence appetite," Gewirtz said.

"The obesity epidemic is driven by people eating too much, but why are people eating more?"

Gewirtz said the research suggests that bacteria may play a role - perhaps a population of bacteria that thrive because other, competing organisms have been wiped out by antibiotics, access to clean water and other factors of modern life.

As if to confirm this, Ed Yong says that "The obesity epidemic is a massive concern for the 21st century. New research shows that the bacteria that live inside our digestive systems could have a large impact on our risk of being obese."

Gerwitz's team stumbled on the findings by accident.

"We were studying mice that had colitis," Gewirtz said in a telephone interview.

The team suspected some kind of germ was responsible, so they transferred mouse embryos into surrogate mothers to prevent them from being infected by their own mothers.

Babies are colonized by bacteria and other micro-organisms soon after birth and the makeup of these colonies - which persist for life in the skin and bowels - are very similar to those of the mother.

The colitis was better but the baby mice became obese and developed metabolic syndrome - a cluster of symptoms that include unhealthy cholesterol levels, too much fat around the midsection, high blood pressure and insulin resistance.

Insulin resistance means the body does not use insulin effectively to break down food and Gewirtz believes this may be the key.

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